The Rhône-Alps Region wants to develop a circular economy through concrete experiments in eco-innovation, efficient design, clean technology and industrial ecology at the regional level. Industrial ecology, a basic constituent in the circular economy, is an integrated approach for testing in the field feedback loops between stakeholders at the local level and identifying key factors, both positive and negative. In 2013, the Rhône-Alps Region, in cooperation with ADEME, issued a call for regional projects: “Industrial and territorial ecology”. Support for two years is offered to territorial subdivisions in the effort to demonstrate this approach’s economic, social and environmental benefits and capitalize on feedback from experiences in order to encourage other territorial subdivisions to come on board.