AN2014231 ART. MANAGEMENT OF SYSTEMIC VASCULITIS

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Article: Management of systemic vasculitis

B. TERRIER, L. GUILLEVIN, L. MOUTHON*
* Service de Médecine Interne, Centre de Référence pour les Maladies Autoimmunes et Systémiques Rares,
Hôpital Cochin, 27 rue du Faubourg Saint-Jacques, 75014 Paris.

Abstract

In the last decades a higher understanding of Systemic Vasculitis has been completed, leading to a better classification of the disease and allowing its patho physiological knowledge to be extended. Many placebo-controlled or prospective trials enabled new molecules to be finalised with specific targets towards either cells or related cytokines. The choice of treatment appears to be founded on diagnosis of vasculitis, as well as underlying patho physiological mechanisms, the severity of lesions and patients’ traits, particularly age and comorbidities. The main objective must be to obtain the best relationship between risks and benefits.

9782747221245
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The example of a mixed economy company has a land development fraud neglected by the literature: there is widespread fraud, little by little, the top-down by imitation and addiction, in collusion implied. Literature was more interested, in fact, illegal maneuvers in the eyes of the officer or prohibited by law. But she had not modeled the process by which fraud is formed, grows and finds an end. Based on the case of the SEM, we propose a model for the dissemination of fraud and we discuss its possible generalization, while analyzing the appropriateness of traditional measures of fight against fraud.

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