The structure of the corpus cavernosum, physiology erection and accessibility of penis make it a model vascular exceptional. The study of hemodynamics Doppler ultrasound can detect smaller vascular lesions and now with PNORT, endothelial dysfunction. The penis appears to be the organ earlier affected by vascular disease. The intracavernous injection of restoring or removing substances erection repair cell or tissue, options are multiple local therapies to treat erectile dysfunction.