Abstract

Objectives: the number of health economic evaluations (ee) increases but their role in decision- making remains unclear. this literature review aims to describe methods used to investigate the use of ee by decision-makers at the macro level; and to analyse the impact of economic evaluations on decision making between developed and developing countries. Methods: Five major databases were searched in seven languages, without time limit, using keywords related to economics, research methods, decision-making and outcomes. titles and abstracts were screened according to four criteria. twenty-nine articles were selected, analysed and compared against a checklist for context, methods and outcomes. Results:Most articles reported single-country studies (n=24) conducted in developed countries (n=20). the target population investigated was mainly composed by health authorities. the following methods were used: questionnaires (n=12), qualitative approaches (n=6), documentary analysis (n =4). Methods triangulation was observed in 6 studies. the use of ee has increased since the late 1990s, though there are differences between countries. ee is mainly encouraged by governmental/institutional incentives. Barriers preventing its wider use are similar among developed and developing countries and mostly related to the accessibility and acceptability of ee. Conclusions: the use of economic evaluations in health-policy decision-making can be enhanced by reducing simple obstacles, e.g. improving the quality of studies through the elaboration of guidelines.

Keywords:

Health economics, decision making, developing/developed countries, Methods; review.